I had a Deployment Manager with two remote nodes federated into it and had left them switched off for over a year now. When I restarted the Deployment Manager the new certificate expiration handling process had renewed the certificates within the 
/opt/IBM/WebSphere/AppServer/profiles/AppSrv01/logs/syncNode.log
ADMU0128I: Starting tool with the AppSrv01 profile
*** SSL SIGNER EXCHANGE PROMPT ***
SSL signer from target host null is not found in trust store /opt/IBM/WebSphere/AppServer/profiles/AppSrv01/etc/trust.p12.
Here is the signer information (verify the digest value matches what is displayed at the server):
Subject DN:    SUBJECT_DN
Issuer DN:     ISSUER_DN
Serial number: SERIAL_NUMBER
Expires:       Sat Oct 16 14:26:05 BST 2010
SHA-1 Digest:  SHA1-DIGEST
MD5 Digest:    MD5-DIGEST
Add signer to the trust store now? (y/n)
Please Note: I have replaced the actual values with some placeholders for obvious security reasons. When I entered yes to this message, it started working fine. In order to keep  these in real sync the easiest option would be create a soft link from PROFILE_ROOT/etc directory to the key.p12 and trust.p12 files within the config/cells/